Article Text

Download PDFPDF

A prediction rule identified patients with atrial fibrillation at low risk of stroke while taking aspirin
Free

Statistics from Altmetric.com


 
 Q What is the accuracy of an age independent clinical prediction rule for identifying patients with non-valvular atrial fibrillation (AF) who are at low risk of all cause stroke or transient ischaemic attack (TIA) while taking aspirin?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory ★★★★★★☆ Geriatrics ★★★★★★☆ Cardiology ★★★★★★☆

METHODS

Embedded ImageDesign:

analysis of data from 6 randomised controlled trials (RCTs) to derive and validate a clinical prediction rule.

Embedded ImageSetting:

US, Canada, Denmark, and the Netherlands.

Embedded ImagePatients:

2501 patients (mean age 70 y, 67% men, 93% white) with non-valvular AF who were participating in 1 of 6 RCTs. All patients had had no stroke or TIA for at least 6–24 months before entering in the trials and received aspirin at dosages between 75–325 mg/day. In most studies, patients were excluded if they had clinical indications for or contraindications to oral anticoagulation or aspirin therapy, or if they had a recent acute coronary syndrome or cardiac revascularisation. Patients were randomly …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.