Statistics from Altmetric.com
Q In children and adolescents with major depressive disorder (MDD), is sertraline more effective than placebo for reducing the severity of patients’ depressive symptoms?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Mental health ★★★★★★★
2 randomised placebo controlled trials with preplanned pooling of results. Patients were stratified into children and adolescents before randomisation.
patients and clinicians.*
Follow up period:
10 weeks of treatment.
53 hospital, general practice, and academic centres in the US, India, Canada, Costa Rica, and Mexico.
376 children and adolescents (age range 6–17 y, 51% girls) who met criteria for MDD according to the DSM-IV and Kiddie Schedule for Affective Disorders and Schizophrenia for School Age Children—Present and Lifetime Version, and had had the current episode of MDD for ⩾6 weeks. Patients were also required to have a …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.