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Oral iron therapy reduced unexplained fatigue in non-anaemic women with serum ferritin concentrations ⩽50 μg/l

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 Q Is iron therapy effective for non-anaemic women with unexplained fatigue?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆


Embedded ImageDesign:

randomised, placebo controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

blinded {patients, clinicians, data collectors, and outcome assessors}.*

Embedded ImageFollow up period:

1 month.

Embedded ImageSetting:

an academic primary care centre and 8 private general practices in western Switzerland.

Embedded ImagePatients:

144 women 18–55 years of age (mean age 35 y, based on n = 136) whose primary reason for consulting was fatigue. Exclusion criteria: anaemia (haemoglobin concentration <117 g/l), other obvious physical or psychiatric causes of fatigue, or chronic fatigue syndrome.

Embedded ImageInterventions:

oral, long acting …

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  • * See glossary.

  • Information provided by author.

  • For correspondence: Dr B Favrat, University of Lausanne, Lausanne, Switzerland.

  • Source of funding: Robapharm.

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