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Q In patients with chronic idiopathic intractable pruritus ani, what is the effectiveness of topical capsaicin?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆
randomised, placebo controlled, crossover trial.
blinded (patients and healthcare providers).*
Follow up period:
4 and 9 weeks.
proctological outpatient clinics in a hospital and affiliated ambulatory clinic in Jerusalem, Israel.
44 patients (mean age 50 y, 55% women) who had chronic idiopathic anal itching for ⩾3 months that had not responded to traditional treatment.
a thin layer of perianal topical capsaicin cream, 0.006% 3 times each day for 4 weeks (n = 22) or menthol cream 1% (placebo) (n = 22). After a 1 week washout period, patients received the alternative treatment for 4 weeks. No patients received topical steroids or anaesthetics …