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Topical nitric oxide relieved pain and symptoms in chronic extensor tendinosis at the elbow

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 Q In patients with chronic extensor tendinosis at the elbow (tennis elbow), does topical nitric oxide improve outcome?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

blinded (patients and outcome assessors).*

Embedded ImageFollow up period:

6 months.

Embedded ImageSetting:

Sydney, New South Wales, Australia.

Embedded ImagePatients:

86 patients (95 elbows) who were 30–74 years of age (median age 46 y, 51% women) and had extensor tendinosis for ⩾3 months. Exclusion criteria: pregnancy, previous surgery, dislocation of the affected wrist or elbow, distal neurological signs, or a local corticosteroid injection in the previous 3 months.

Embedded ImageIntervention:

43 patients were allocated to an active transdermal patch (1/4 of a 5 mg …

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  • * See glossary.

  • Information provided by author.

  • For correspondence: Professory G A C Murrell, University of New South Wales, Sydney, New South Wales, Australia.

  • Source of funding: in part, St George Hospital—South Eastern Sydney Area Health Services.

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