THERAPEUTICS
Bruce ML, Ten Have TR, Reynolds CF 3rd, et al. Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: a randomized controlled trial. JAMA 2004;291:1081–91.
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Mental health ★★★★★☆☆ IM/Ambulatory care ★★★★★☆☆ Geriatrics ★★★★☆☆☆
Hsia J, Criqui MH, Rodabough RJ, et al. Estrogen plus progestin and the risk of peripheral arterial disease: the Women’s Health Initiative. Circulation 2004;109:620–6.
Clinical impact ratings GP/FP/Primary Care ★★★★★☆☆ IM/Ambulatory care ★★★★☆☆☆ Cardiology ★★★★☆☆☆
Helfand M. Screening for subclinical thyroid dysfunction in nonpregnant adults: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2004;140:128–41.
Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★☆☆ Endocrine ★★★★☆☆☆
Aljabri K, Kozak SE, Thompson DM. Addition of pioglitazone or bedtime insulin to maximal doses of sulfonylurea and metformin in type 2 diabetes patients with poor glucose control: a prospective, randomized trial. Am J Med 2004;116:230–5.
Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★☆☆ Endocrine ★★★★☆☆☆
Larson EL, Lin SX, Gomez-Pichardo C, et al. Effect of antibacterial home cleaning and handwashing products on infectious disease symptoms: a randomized, double-blind trial. Ann Intern Med 2004;140:321–9.
Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Infectious disease ★★★★☆☆☆
Correll CU, Leucht S, Kane JM. Lower risk for tardive dyskinesia associated with second-generation antipsychotics: a systematic review of 1-year studies. Am J Psychiatry 2004;161:414–25.
Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Mental health ★★★★☆☆☆ IM/Ambulatory care ★★☆☆☆☆☆ Psychiatry ★★★★★★☆
Rubin BR, Burton R, Navarra S, et al. Efficacy and safety profile of treatment with etoricoxib 120 mg once daily compared with indomethacin 50 mg three times daily in acute gout: a randomized controlled trial. Arthritis Rheum 2004;50:598–606.
Clinical impact ratings GP/FP/Primary Care ★★★★★☆☆ IM/Ambulatory care ★★★★☆☆☆ Rheumatology ★★★★☆☆☆
Teunissen TA, de Jonge A, van Weel C, et al. Treating urinary incontinence in the elderly—conservative therapies that work: a systematic review. J Fam Pract 2004;53:25–30, 32.
Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Geriatrics ★★★☆☆☆☆
Karjalainen K, Malmivaara A, Mutanen P, et al. Mini-intervention for subacute low back pain: two-year follow-up and modifiers of effectiveness. Spine 2004;29:1069–76.
Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Physical medicine and rehabilitation ★★★★★☆☆
Panzuto F, Di Giulio E, Capurso G, et al. Large hiatal hernia in patients with iron deficiency anaemia: a prospective study on prevalence and treatment. Aliment Pharmacol Ther 2004;19:663–70.
Clinical impact ratings Gastroenterology ★★★★★☆☆
Ohgi S, Akiyama T, Arisawa K, et al. Randomised controlled trial of swaddling versus massage in the management of excessive crying in infants with cerebral injuries. Arch Dis Child 2004;89:212–6.
Clinical impact ratings Paediatrics ★★★★★☆☆
Staessen JA, Den Hond E, Celis H, et al. Antihypertensive treatment based on blood pressure measurement at home or in the physician’s office: a randomized controlled trial. JAMA 2004;291:955–64.
Clinical impact ratings GP/FP/Primary care ★★★★☆☆☆IM/Ambulatory care ★★★★★☆☆ Cardiology ★★★★★☆☆ Endocrine ★★★★☆☆☆ Geriatrics ★★★☆☆☆☆ Nephrology ★★★★★☆☆
Holdgate A, Pollock T. Nonsteroidal anti-inflammatory drugs (NSAIDs) versus opioids for acute renal colic. Cochrane Database Syst Rev 2004;(1):CD004137.
Clinical impact ratings Internal medicine ★★★★☆☆☆ Emergency medicine ★★★★☆☆☆ Nephrology ★★★☆☆☆☆
Kariminia A, Chamberlain ME, Keogh J, et al. Randomised controlled trial of effect of hands and knees posturing on incidence of occiput posterior position at birth. BMJ 2004;328:490.
Clinical impact ratings FP/GP/Obstetrics ★★★★★☆☆ Obstetrics ★★★★☆☆☆
Hurwitz EL, Morgenstern H, Vassilaki M, et al. Adverse reactions to chiropractic treatment and their effects on satisfaction and clinical outcomes among patients enrolled in the UCLA Neck Pain Study. J Manipulative Physiol Ther 2004;27:16–25.
Clinical impact ratings GP/FP/Primary care ★★★★☆☆☆ Rheumatology ★★★☆☆☆☆
Naredo E, Cabero F, Beneyto P, et al. A randomized comparative study of short term response to blind injection versus sonographic-guided injection of local corticosteroids in patients with painful shoulder. J Rheumatol 2004;31:308–14.
Clinical impact ratings GP/FP/Primary care ★★★★☆☆☆ Rheumatology ★★★★★☆☆
Huibers MJ, Beurskens AJ, Van Schayck CP, et al. Efficacy of cognitive-behavioural therapy by general practitioners for unexplained fatigue among employees: randomised controlled trial. Br J Psychiatry 2004;184:240–6.
Clinical impact ratings GP/FP/Primary care ★★★★☆☆☆ Mental health ★★★☆☆☆☆ Psychiatry ★★☆☆☆☆☆
Stellbrink C, Nixdorff U, Hofmann T, et al. Safety and efficacy of enoxaparin compared with unfractionated heparin and oral anticoagulants for prevention of thromboembolic complications in cardioversion of nonvalvular atrial fibrillation: the Anticoagulation in Cardioversion using Enoxaparin (ACE) trial. Circulation 2004;109:997–1003.
Clinical impact ratings IM/Ambulatory care ★★★★☆☆☆ Cardiology ★★★★★★☆ Haematology ★★★★★☆☆
Ziaei S, Hosseiney FS, Faghihzadeh S. The efficacy low dose of prednisolone in the treatment of hyperemesis gravidarum. Acta Obstet Gynecol Scand 2004;83:272–5.
Clinical impact ratings GP/FP/Obstetrics ★★★★☆☆☆ Obstetrics ★★★☆☆☆☆
Ma SH, Teasdale JD. Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects. J Consult Clin Psychol 2004;72:31–40.
Clinical impact ratings Mental health ★★★★☆☆☆ Psychiatry ★★★☆☆☆☆
Carroll KM, Fenton LR, Ball SA, et al. Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial. Arch Gen Psychiatry 2004;61:264–72.
Clinical impact ratings GP/FP/Primary care ★★★☆☆☆☆
Subramanian U, Fihn SD, Weinberger M, et al. A controlled trial of including symptom data in computer-based care suggestions for managing patients with chronic heart failure. Am J Med 2004;116:375–84.
Clinical impact ratings GP/FP/Primary Care ★★★☆☆☆☆ IM/Ambulatory care ★★★★☆☆☆ Cardiology ★★★☆☆☆☆
Roy M, Bailey B, Amre DK, et al. Dexamethasone for the treatment of sore throat in children with suspected infectious mononucleosis: a randomized, double-blind, placebo-controlled, clinical trial. Arch Pediatr Adolesc Med 2004;158:250–4.
Clinical impact ratings GP/FP/Primary care ★★★☆☆☆☆ Infectious Disease ★★★☆☆☆☆ Paediatrics ★★★★★☆☆
Cummings JL, Schneider L, Tariot PN, et al. Reduction of behavioral disturbances and caregiver distress by galantamine in patients with Alzheimer’s disease. Am J Psychiatry 2004;161:532–8.
Clinical impact ratings GP/FP/Primary care ★★★☆☆☆☆ Internal medicine ★★★★☆☆☆ Mental health ★★★★☆☆☆ Geriatrics ★★★★★★☆
Stuge B, Laerum E, Kirkesola G, et al. The efficacy of a treatment program focusing on specific stabilizing exercises for pelvic girdle pain after pregnancy. Spine 2004;29:351–9.
Clinical impact ratings FP/GP/Obstetrics ★★★☆☆☆☆ Obstetrics ★★★★☆☆☆
Wang C, Collet JP, Lau J. The effect of Tai Chi on health outcomes in patients with chronic conditions: a systematic review. Arch Intern Med 2004;164:493–501.
Clinical impact ratings GP/FP/Primary care ★★★☆☆☆☆
Ziegler D, Nowak H, Kempler P, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis. Diabet Med 2004;21:114–21.
Clinical impact ratings IM/Ambulatory care ★★☆☆☆☆☆ Endocrine ★★★★★☆☆ Neurology ★★★★★☆☆
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