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The BODE index predicted death in chronic obstructive pulmonary disease

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 Q In patients with chronic obstructive pulmonary disease (COPD), how well does an index comprising the risk factors that reflect the respiratory, perceptive, and systemic aspects of the disease predict outcome?

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Embedded ImageDesign:

2 cohort studies, 1 for development and 1 for validation.

Embedded ImageSetting:

clinics in the US, Venezuela, and Spain.

Embedded ImagePatients:

832 patients (mean age 66 y) who had COPD with a wide range of severity, were in clinically stable condition, and were receiving appropriate therapy. Exclusion criteria: probability of death within 3 years from a cause other than COPD, asthma, inability to take the lung function and 6 minute walk tests, myocardial infarction within the previous 4 months, unstable angina, or congestive heart failure. 207 patients were recruited from 1995 to 1997 and formed the development cohort; 625 patients were recruited from 1997 to 2003 …

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  • For correspondence: Dr B R Celli, St. Elizabeth’s Medical Center, Tufts University School of Medicine, Boston, MA, USA.

  • Source of funding: no external funding.