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  • Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo

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Therapeutics
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo

https://doi.org/10.1136/ebm.9.6.176

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    Koning S, Verhagen AP, van Suijlekom-Smit LW, et al. Interventions for impetigo. Cochrane Database Syst Rev 2004;(2):CD003261.

    
 
 Q Which treatments are effective for impetigo?

    Clinical impact ratings Dermatology ★★★★★★☆ GP/FP/Primary care ★★★★★☆☆

    METHODS

    Embedded ImageData sources:

    Cochrane Skin Group Specialised Trials Register (March 2002), Cochrane Central Register of Controlled Trials (Issue 1, 2002), National Research Register (2002), Medline (1966 to January 2003), EMBASE/Excerpta Medica (1980 to March 2000), LILACS (November 2001), and metaRegister of Controlled Trials on the Current Controlled Trials website; hand searches of Yearbook of Dermatology (1938–66) and Yearbook of Drug Therapy (1949–66); reference lists; and contact with trial authors and pharmaceutical companies.

    Embedded ImageStudy selection and assessment:

    published and unpublished randomised controlled trials (RCTs) in any language that assessed any intervention for impetigo (non-bullous, bullous, secondary, and impetiginised dermatoses) in patients with diagnosed impetigo, preferably confirmed by bacterial culture; studies that assessed patients with broadly defined bacterial skin infections or pyoderma were included if results for patients with impetigo were reported separately. 2 independent reviewers assessed the methodological quality of individual trials.

    Embedded ImageOutcome:

    clinical cure …

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