Article Text
Harms
Systematic review and meta-analysis
Combined oral contraceptives increase risk of venous thrombosis according to oestrogen dose and type of progestogen
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Context
There is compelling evidence that use of combined oral contraceptives (COCs) is associated with a two-to-fourfold increased risk of venous thrombosis (ie, either deep venous thrombosis or pulmonary embolism).1 Although the risks have been assessed for various combinations of oestrogen dose and type of progestogen in COCs, the findings of these assessments have been debated and a comprehensive comparison of the commonly used COCs has …
Footnotes
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Competing interests None.
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Provenance and peer review Commissioned; internally peer reviewed.