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Randomised controlled trial
Clinical outcomes following coronary CT angiography are comparable to radionuclide myocardial perfusion imaging for ethnically diverse intermediate risk acute chest pain inpatients
  1. Hampton Crimm1,
  2. Edward Hulten1,2
  1. 1Department of Medicine (Cardiology Service), Walter Reed National Military Medical Center, Bethesda, Maryland, USA;
  2. 2Non-Invasive Cardiovascular Imaging Program, Departments of Medicine (Cardiovascular Division) and Radiology, Brigham and Women's Hospital and Harvard Medical School, Bethesda, Maryland, USA
  1. Correspondence to : Dr Edward Hulten, Department of Medicine (Cardiology Service), Walter Reed National Military Medical Center, Bethesda, MD 20889, USA; ehulten{at}

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Since the evolution of 64-multidetector CT in the early 2000s, use of coronary CT angiography (CCTA) has experienced rapid expansion due to excellent sensitivity to exclude obstructive coronary artery disease (CAD) in low to intermediate risk chest pain patients.1 Prior studies of acute chest pain patients have demonstrated a diagnostic strategy using CCTA to have comparable safety to usual care evaluation, generally radionuclide myocardial perfusion imaging (MPI), with the potential for more rapid triage but an increased rate of invasive coronary angiography (ICA) and revascularisation.2 Prior CCTA trials, like most cardiovascular studies, have enrolled predominantly Caucasian men.


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