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Commentary on: Goadsby PJ, Reuter U, Hallström YA, et al. A Controlled Trial of Erenumab for Episodic Migraine. N Engl J Med. 2017;377:2123-2132.
Migraine presents an important social, economic and disability burden in 14% of affected population.1 The age range more compromised is under 50, which represents a burden in personal, social and working functioning.1
Migraine treatments are old and with low compliance by the patient for adverse events. Erenumab is a fully human monoclonal antibody that inhibits the calcitonin gene-related peptide receptor (CGRPr) showing promising evidences from a controlled trial in episodic migraine.2
This randomised, double-blind, multicentre, placebo-controlled trial of erenumab in episodic migraine has been carried out through the monthly subcutaneous administration of either erenumab or placebo for a 6-month period. In total, …
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