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General medicine
Understanding Risk for Better Stroke Prevention
  1. Gustavo Saposnik1,2,3
  1. 1 Department of Economics, University of Zurich, Zürich, Switzerland
  2. 2 Outcomes Research and Decision-Neuroscience Unit, Department of Medicine, St Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada
  3. 3 Department of Cardiovascular Diseases, Institute for Clinical Evaluative Sciences (ICES), Toronto, Ontario, Canada
  1. Correspondence to Dr. Gustavo Saposnik, Outcomes Research and Decision-Neuroscience Unit, Department of Medicine, St Michael’s Hospital, University of Toronto, Toronto, ON M5C 1R6, Canada; saposnikg{at}smh.ca

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Commentary on: Amarenco P, Lavallée PC, Monteiro Tavares L, et al. Five-year risk of stroke after TIA or minor ischemic stroke. N Engl J Med. 2018;378:2182–2190

“Living at risk is jumping off the cliff and building your wings on the way down. Ray Bradbury (1920-2012)

Context

Over the last three decades, we learnt about the value of risk stratification tools (eg, ABCD2, Oxford TIA, among others) that may help guide management decisions.1 However, limited information is available on the recurrence of cardiovascular events, stroke, death 5 years after a transient ischaemic attack (TIA) or minor stroke.2 The TIAregistry.org prospectively included patients with a recent TIA or minor stroke to evaluate the short-term (3 months and 1 year) and long-term (5 years) outcomes.3

Methods

The authors prospectively collected data on patients aged 18 years and older with a recent diagnosis of TIA or minor stroke (less than 7 days) from 21 …

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