Article Text

PDF
Primary care
Pivmecillinam is more effective than ibuprofen in symptom resolution in women with uncomplicated urinary tract infection: antibiotic treatment for UTI is important
  1. Jutta Bleidorn
  1. Department of General Practice, Medical School Hannover, Hannover, Germany
  1. Correspondence to Dr Jutta Bleidorn, Department of General Practice, Medical School Hannover, Germany; bleidorn.jutta{at}mh-hannover.de

Statistics from Altmetric.com

Commentary on: Vik I, Bollestad M, Grude N, et al. Ibuprofen versus pivmecillinam for uncomplicated urinary tract infection in women—a double-blind, randomized non-inferiority trial. PLoS Med. 2018;15:e1002569.

Context

Uncomplicated urinary tract infection (UTI) is a common condition, and many affected women are treated with antibiotics. However, since complications are rare, the main treatment goal is to reduce symptoms.1 Several trials indicate that many patients recover with symptomatic treatment or delayed prescription,2 3 and reducing avoidable antibiotic prescriptions gains in importance to decrease resistance development.4 5 Against this background, Vik et al conducted this randomised controlled trial to assess non-inferiority of symptomatic treatment of uncomplicated UTI.6 Nearly simultaneously, similar trials assessed fosfomycin versus ibuprofen7 respectively norfloxacin versus diclofenac8 in treatment of uncomplicated UTI.

Methods

To assess whether …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.