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Commentary on: Hall PS, Mitchell ED, Smith AF, et al. The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation. Health Technol Assess. 2018;22:1–274.
Acute kidney injury (AKI) is a common condition in hospitalised patients and is associated with worse short-term and long-term outcome. The delay in the diagnosis of AKI has been proven to be associated with morbidity and mortality. One of the challenges clinicians face is the early detection of AKI. Another difficulty is the lack of a consensual definition of AKI. Expert consensus seems to be emerging,1 but recent literature review shows that the definitions used in the published articles remain multiple and heterogeneous.2 While many urinary and serum proteins have been investigated as potential biomarkers for the early diagnosis or …
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