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In the first half of this year, an article about the next generation of evidence-based medicine1 was published in Nature Medicine, emphasising the growing significance of real-world data in future evidence-based practice and research, providing an opportunity for the evidence accumulation of dynamic intervention (DI) strategies (spanning sequential designs to real-time feedback protocols) in various diseases, as is patient-centric, adaptable and pivotal for modern patient care.
Most intervention meta-analyses address static interventions, diverging from dynamic clinical practices in multistage diseases such as the facial neuritis, primarily comparing positive interventions to controls or other therapies, overlooking real-world adaptive strategies used at different disease stages. For facial neuritis, the early stage may benefit more from gentle acupuncture and …
Contributors TP searched relevant literature and drafted the work and PZ contributed to the conception, work design and review. Both authors agreed to be accountable for the work involving the accuracy or integrity.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.