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Opinion
Enhancing the transparency of clinical practice guidelines by prospective registration: the PREPARE platform
  1. Hui Liu1,
  2. Nan Yang1,
  3. Janne Estill2,3,
  4. Yaolong Chen1,4
  1. 1Research Unit of Evidence-Based Evaluation and Guidelines (2021RU017), Chinese Academy of Medical Sciences, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu, China
  2. 2Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu, China
  3. 3Institute of Global Health, University of Geneva, Geneva, Switzerland
  4. 4WHO Collaborating Centre for Guideline Implementation and Knowledge Translation, Lanzhou, Gansu, China
  1. Correspondence to Professor Yaolong Chen, Research Unit of Evidence-Based Evaluation and Guidelines (2021RU017), Chinese Academy of Medical Sciences, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu 730000, China; chevidence{at}lzu.edu.cn

https://doi.org/10.1136/bmjebm-2023-112813

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    Prospective registration of clinical practice guidelines has received increasing attention from researchers in recent years.1–3 Registration means submitting information such as the title, purpose, developer, methodology and conflicts of interest of a planned guideline to a publicly accessible registration platform before commencing the development.4 Registration can reduce unnecessary duplication, increase transparency, improve the quality of guidelines and facilitate guideline dissemination, which in turn can be of great benefit for guideline developers, researchers, peer reviewers, editors, clinicians and other guidelines users.1 PREPARE (Practice guideline REgistration for transPAREncy, http://guidelines-registry.org) is a registration platform for guidelines that is free of charge for all guideline developers globally.4 This article will provide a detailed introduction to the PREPARE platform.

    What are the current policies related to guideline registration?

    The Association of Scientific Medical Societies in Germany (AWMF) and Australian National Health and Medical Research Council (NHMRC) require all guidelines to be preregistered on their respective platforms in order to be later approved by the organisation. The new edition of the guidance for development or revision of clinical diagnosis and treatment guidelines issued by the Chinese Medical Association in 2022 explicitly mentions the need for prospective registration of guidelines.5 Several societies, such as the Egyptian Pediatric Clinical Practice Guidelines Committee and …

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    Footnotes

    • Contributors HL and YC conceived and designed the study. HL and NY wrote the manuscript, analysed the data and produced the figures. JE and YC revised the manuscript.

    • Funding This work was supported by the Fundamental Research Funds for the Central Universities (lzujbky-2021-ey13) and the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences-Research Unit of Evidence-Based Evaluation and Guidelines (2021RU017).

    • Competing interests YC is the co-founder of PREPARE (Practice guideline REgistration for transPAREncy).

    • Provenance and peer review Not commissioned; externally peer reviewed.