eLetters

138 e-Letters

  • 'Cognitive biases plus' and healthcare evidence
    Shashi S. Seshia

    Dear Editor,

    Mazar and Ariely's recent paper [1] reinforces the concepts and suggestions discussed in our recent publications: dishonesty is a human universal, and there is no one-size-fits-all solution [2,3]. Education, moral reminders and changing how researchers are rewarded are important tools [1]. Most importantly, we need to reclaim the integrity, dedication and code of honor Sir Austin Bradford Hill consider...

    Show More
  • Author's response
    Kit Byatt

    Dear Editor,

    I am very grateful to Ken Uchino for amplifying and clarifying the detail of some of the points I was trying to make within the word limits of a 'Perspectives' paper. I suggest there are four key elements:

    1. The epidemiology is indeed complex and I am neither an academic nor an epidemiologist. However, it would appear that we can agree that there is indeed a difference between 'younger old'...

    Show More
  • Overreacting to possible over-treatment? Hypertension treatment in the very elderly.
    Ken Uchino

    Dear Editor,

    While I agree with Dr Byatt that it is important to discuss with patients the choices of treating risk factors to prevent disease, the basis for the discussion needs to be clarified and fine-tuned.

    Epidemiology: The attributable risk of hypertension in stroke decreases in the elderly. This phenomenon may be partly because other factors such as atrial fibrillation become more dominant factor....

    Show More
  • Re:DPP4is are safe
    Joshua J. Fenton

    Dear Editor,

    Andrea Giaccari asserts that I wrote in my editorial that sitagliptin in the TECOS trial "caused" 20% increase in the secondary outcome of congestive heart failure. That is not what I wrote. I wrote that "the study data remain consistent with" a 20% increase in this adverse outcome. While the wide confidence interval is also consistent with a reduction in heart failure risk, the primary goal of the TECOS tr...

    Show More
  • DPP4is are safe
    Andrea Giaccari

    Dear Editor,

    I read with interest the comments of Dr. Fenton. In his editorial (Evid Based Med. 2016 Jun;21(3):81-2) Dr Fenton stated that sitagliptin caused in TECOS "a 20% increase in the secondary outcome of congestive heart failure (intention-to-treat HR 1.00, 95% CI 0.82 to 1.20, p=0.98)". This is really misleading. With exactly the same numbers Dr. Fenton could state that sitagliptin caused an 18% reduction in hos...

    Show More
  • Opinion editorials: necessity of present times
    Pankaj Jorwal

    Dear Editor,

    This article brings into light the upcoming ways in which medical health care knowledge is disseminated between general population and the various pitfalls such an approach can have. Although such issues are in nascent stage in a developing country like India but its climbing up the ladder at a brisk rate. The new generation of physicians is media savvy but can get easily influenced by media based...

    Show More
  • In Response to Windish D. "EBM apps that help you search for answers to your clinical questions."
    Gavriel D. Kohlberg

    Dear Editor,

    We read with great interest the recent article by Dr. Windish [1] reviewing a number of Evidence-Based Medicine (EBM) smartphone apps. Immediate access to brief summaries of the literature is essential in bringing EBM knowledge to the bedside, as physicians are often busy and are presented with frequent interruptions which hinder their ability to perform detailed searches or read complete articles dur...

    Show More
  • Maternal pertussis vaccination
    Elyse O Kharbanda

    Dear Editor,

    We were pleased to read the commentary by Millar and Sanz(1) regarding our publication on Tdap safety in pregnancy from the Vaccine Safety Datalink.(2) We agree that policies regarding routine vaccination should be made after careful review of the risks and benefits of vaccination. For maternal vaccination, evaluations of risk-benefit profiles are complex, as both maternal and infant outcomes must be...

    Show More
  • Judging evidence in postoperative analgesia
    Andrew Moore

    Dear Editor,

    First, thank you for highlighting our paper. However, I do want to take issue with this commentary.

    Systematic reviews in postop analgesia have been done now for over 20 years, and there is considerable methodological research to substantiate what is done. The results are robust and trustworthy.

    Single trials, however well done, are not trustworthy because while they may be powered t...

    Show More
  • Editors' Reply to eLetter from JC Platt
    EBM Editors

    Dear Mr Platt

    Many thanks for your eLetter regarding an abstract appearing in both EBM[1] and EBN[2] with different commentaries. In answer to your queries:
    First, when we have the same abstract appearing in both journals we do sometimes use the same commentary as well, however, if we think it doesn't fit our target audience we can require a fresh commentary. The risk is that, like all opinion, diff...

    Show More

Pages