TY - JOUR T1 - Age, impaired fasting glucose, and cirrhosis predicted mortality at mean 7.6 years for non-alcoholic fatty liver disease JF - Evidence Based Medicine JO - Evid Based Med SP - 26 LP - 26 DO - 10.1136/ebm.11.1.26 VL - 11 IS - 1 A2 - , Y1 - 2006/02/01 UR - http://ebm.bmj.com/content/11/1/26.abstract N2 - Adams LA, Lymp JF, St Sauver J, et al. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005;129:113–21.OpenUrlCrossRefPubMedWeb of Science 
 
 Q What is the natural history of non-alcoholic fatty liver disease (NAFLD) in community based patients? Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★☆☆ Gastroenterology ★★★★★☆☆ Design: inception cohort followed for mean 7.6 years (range 0.1–23.5 y). Setting: Olmsted County in southeastern Minnesota, USA. Patients: 435 patients (mean age 49 y, 51% women, 92% white) diagnosed with NAFLD, fatty liver, hepatic steatosis, steatohepatitis, or cryptogenic cirrhosis (confirmed by ultrasonography, computed tomography, or magnetic resonance imaging) between 1 January 1980 and 1 January 2000. Exclusion criteria included other liver disease, risk of viral hepatitis, secondary causes of fatty liver (medications, human immunodeficiency virus, or gastrointestinal bypass surgery), and average weekly ethanol consumption ⩾140 g. Prognostic factors: age, sex, ethnicity, body mass index, average weekly alcohol intake, history of diabetes (fasting glucose ⩾126 mg/dl [6.93 mmol/l] or receiving treatment), impaired fasting glucose (IFG) (fasting glucose ⩾110 mg/dl [6.05 … ER -