TY - JOUR T1 - Review: antibiotics active against atypical pathogens do not improve community acquired pneumonia more than β lactam antibiotics JF - Evidence Based Medicine JO - Evid Based Med SP - 115 LP - 115 DO - 10.1136/ebm.10.4.115 VL - 10 IS - 4 A2 - , Y1 - 2005/08/01 UR - http://ebm.bmj.com/content/10/4/115.abstract N2 - Mills GD, Oehley MR, Arroll B. Effectiveness of β lactam antibiotics compared with antibiotics active against atypical pathogens in non-severe community acquired pneumonia: meta-analysis. BMJ 2005;330:456.OpenUrlAbstract/FREE Full Text 
 
 Q In patients with community acquired pneumonia (CAP), how do antibiotics active against atypical pathogens (AAAAPs) compare with β lactam antibiotics for effectiveness? Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★★☆ Infectious disease ★★★★★★☆ Data sources: Cochrane Central Controlled Trials Register, Medline, and EMBASE/Excerpta Medica (to December 2003); conference proceedings; registration authorities; reference lists of review articles and retrieved studies; and pharmaceutical companies conducting trials on AAAAPs. Study selection and assessment: randomised, blinded (investigators, patients, and outcome assessors), controlled trials (RCTs) that compared AAAAPs (fluoroquinolones, macrolides, and ketolides) with β lactam antibiotics (penicillins and cephalosporins) in patients with radiographically confirmed CAP. Outcomes: failure to achieve clinical cure or improvement and all cause … ER -