TY - JOUR T1 - Ibuprofen was more effective than codeine or acetaminophen for musculoskeletal pain in children JF - Evidence Based Medicine JO - Evid Based Med SP - 144 LP - 144 DO - 10.1136/ebm.12.5.144 VL - 12 IS - 5 A2 - , Y1 - 2007/10/01 UR - http://ebm.bmj.com/content/12/5/144.abstract N2 - Clark E, Plint AC, Correll R, et al. A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. Pediatrics 2007;119:460–7.OpenUrlAbstract/FREE Full Text 
 
 Q In children with musculoskeletal pain, what is the relative efficacy of ibuprofen, acetaminophen, and codeine? Clinical impact ratings Paediatrics ★★★★★★★ Emergency medicine ★★★★★★☆ Paediatric emergency medicine ★★★★★☆☆ Design: randomised controlled trial. Allocation: {concealed}*.† Blinding: blinded (patients [children and parents], {healthcare providers}*, and data collectors).† Follow up period: 120 minutes. Setting: the emergency department of an academic, tertiary care children’s hospital in Ottawa, Ontario, Canada. Patients: 336 children 6–17 years of age (mean age 12 y, 60% boys) presenting to the emergency department with pain from a musculoskeletal injury to extremities, neck, or back that occurred in the previous 48 hours. Exclusion criteria included contraindication to a study drug, receipt of 1 of the study drugs in … ER -