TY - JOUR T1 - Review: vaccines prevent influenza and influenza-like illness in healthy children >2 years of age JF - Evidence Based Medicine JO - Evid Based Med SP - 140 LP - 140 DO - 10.1136/ebm.11.5.140 VL - 11 IS - 5 A2 - , Y1 - 2006/10/01 UR - http://ebm.bmj.com/content/11/5/140.abstract N2 - Smith S, Demicheli V, Di Pietrantonj C, et al. Vaccines for preventing influenza in healthy children. Cochrane Database Syst Rev 2006;(1):CD004879. 
 
 Q In healthy children <16 years of age, are influenza vaccines efficacious (ie, prevent confirmed influenza) and effective (ie, prevent influenza-like illness)? Data sources: Medline (1966–2004), EMBASE/Excerpta Medica (1974–2004), Cochrane Library (Issue 1, 2005), Biological Abstracts (1969–2004), Science Citation Index (1974–2004), Vaccine Adverse Event Reporting System website (www.vaers.org), and vaccine manufacturers and authors of relevant studies. Study selection and assessment: randomised controlled trials (RCTs) or semi-randomised, cohort, and case controlled studies in any language that enrolled healthy children <16 years of age in any geographical location; compared any influenza vaccine (including unlicensed types) given independently, in any dose, preparation, or time schedule, with placebo or no intervention. 51 studies (n = 263 987) met the selection criteria: 14 RCTs and 11 cohort studies assessed vaccine efficacy and … ER -