TY - JOUR T1 - Calcium did not prevent fractures in elderly women JF - Evidence Based Medicine JO - Evid Based Med SP - 149 LP - 149 DO - 10.1136/ebm.11.5.149 VL - 11 IS - 5 A2 - , Y1 - 2006/10/01 UR - http://ebm.bmj.com/content/11/5/149.abstract N2 - Prince RL, Devine A, Dhaliwal SS, et al. Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women. Arch Intern Med 2006;166:869–75.OpenUrlCrossRefPubMedWeb of Science 
 
 Q In ambulatory elderly women unselected for low bone mass, does calcium supplementation reduce the risk of fractures? Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Public health ★★★★★★☆ Geriatrics ★★★★★☆☆ Design: randomised, placebo controlled trial. Allocation: concealed.* Blinding: blinded {patients, healthcare providers, data collectors, and outcome assessors}†.* Follow up period: 5 years. Setting: population-based study in Western Australia. Participants: 1460 ambulatory women >70 years of age (mean age 75 y) who were not taking any medication affecting bone mass and were expected to survive >5 years. Intervention: calcium carbonate, 600 mg twice daily with meals (n = 730), or placebo (n = 730). Outcomes: incident atraumatic clinical fractures and symptomatic vertebral fractures (self reported and confirmed by radiographic reports), and adverse events requiring medical attention. … ER -