TY - JOUR T1 - Review: BP-lowering drugs prevent cardiovascular events equally well in younger and older patients JF - Evidence Based Medicine JO - Evid Based Med SP - 174 LP - 174 DO - 10.1136/ebm.13.6.174 VL - 13 IS - 6 A2 - , Y1 - 2008/12/01 UR - http://ebm.bmj.com/content/13/6/174.abstract N2 - F TurnbullDr F Turnbull, University of Sydney, Sydney, New South Wales, Australia; fturnbull@george.org.auAre different classes of drugs to lower blood pressure (BP) similarly effective for preventing major cardiovascular events in younger (<65 y) and older (⩾65 y) patients?Included studies compared drugs that lower BP with placebo, a less-intensive BP-lowering regimen, or a different class of BP-lowering drug. Primary outcome was major cardiovascular event (fatal or non-fatal stroke, myocardial infarction, or heart failure).In a prespecifed protocol, the review was to include ongoing or planned randomised controlled trials (RCTs) that had ⩾1000 patient-years of planned follow-up per group and no results presented before July 1995 (date of protocol finalisation). Of 37 eligible trials, individual patient data were provided for 25 RCTs … ER -