TY - JOUR T1 - Cognitive therapy reduced relapses and number of days in bipolar episodes in <em>DSM-IV</em> bipolar I disorder JF - Evidence Based Medicine JO - Evid Based Med SP - 145 LP - 145 DO - 10.1136/ebm.10.5.145 VL - 10 IS - 5 A2 - , Y1 - 2005/10/01 UR - http://ebm.bmj.com/content/10/5/145.abstract N2 - Lam DH, Hayward P, Watkins ER, et al. Relapse prevention in patients with bipolar disorder: cognitive therapy outcome after 2 years. Am J Psychiatry 2005;162:324–9.OpenUrlCrossRefPubMedWeb of Science 
 
 Q In patients with DSM-IV bipolar I disorder, is medication plus cognitive therapy (CT) more effective than medication alone for reducing relapses and number of days in bipolar episodes? Design: randomised controlled trial. Allocation: concealed.* Blinding: blinded (outcome assessors).* Follow up period: 30 months. Setting: Institute of Psychiatry, King’s College, London, UK. Patients: 103 patients (mean age 44 y, 56% women) who met DSM-IV criteria for bipolar I disorder. Patients were also required to have had ⩾2 episodes in the last 2 years or 3 episodes in the last 5 years. Actively suicidal or patients with a current substance use disorder were … ER -