TY - JOUR T1 - Herbal supplements did not relieve vasomotor symptoms of menopause in women JF - Evidence Based Medicine JO - Evid Based Med SP - 78 LP - 78 DO - 10.1136/ebm.12.3.78 VL - 12 IS - 3 A2 - , Y1 - 2007/06/01 UR - http://ebm.bmj.com/content/12/3/78.abstract N2 - Newton KM, Reed SD, LaCroix AZ, et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med 2006;145:869–79.OpenUrlCrossRefPubMed 
 
 Q Do herbal supplements relieve vasomotor symptoms of menopause in women? Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Design: randomised placebo controlled trial (Herbal Alternatives for Menopause Trial [HALT]). Allocation: concealed.* Blinding: blinded (clinicians, participants, {data collectors, and outcome assessors}†).* Follow up period: 12 months. Setting: Washington State, USA. Patients: 351 women 45–55 years of age (mean age 52 y, 93% white) who were in menopausal transition or postmenopausal with ⩾2 vasomotor symptoms per day for 2 weeks (⩾6 moderate to severe symptoms). Exclusion criteria included contraindications to hormone therapy (HT), use of HT or oral contraceptives in the past 3 months, use of herbal medicines in the past month, bilateral oophorectomy, or history of breast cancer. Intervention: black cohosh (Actaea racemosa or Cimicifuga racemosa), 160 … ER -