TY - JOUR T1 - Percutaneous coronary intervention plus optimal medical therapy was not more effective than medical therapy alone in stable CAD JF - Evidence Based Medicine JO - Evid Based Med SP - 107 LP - 107 DO - 10.1136/ebm.12.4.107 VL - 12 IS - 4 A2 - , Y1 - 2007/08/01 UR - http://ebm.bmj.com/content/12/4/107.abstract N2 - Boden WE, O’Rourke RA, Teo KK, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med 2007;356:1503–16.OpenUrlCrossRefPubMed 
 
 Q In patients with stable coronary artery disease (CAD), is percutaneous coronary intervention (PCI) plus optimal medical therapy (OMT) more effective for preventing cardiovascular events than OMT alone? Clinical impact ratings GP/FP/Primary care ★★★★★★★ Internal medicine ★★★★★★☆ Cardiology ★★★★★★☆ Design: randomised controlled trial (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE] trial). Allocation: unclear allocation concealment.* Blinding: blinded (outcome adjudication committee).* Follow up period: median 4.6 years (range 2.5–7.0 y). Setting: 50 centres in the US and Canada. Patients: 2287 patients (mean age 62 y, 85% men) with stable CAD (stenosis ⩾70% in ⩾1 proximal epicardial coronary artery and objective evidence of myocardial ischaemia, or ⩾1 coronary stenosis ⩾80% and classic angina without provocative testing). Exclusion criteria included persistent class IV angina, a markedly positive stress test, refractory heart failure or cardiogenic shock, ejection fraction <30%, revascularisation in ⩽6 … ER -