TY - JOUR T1 - CT pulmonary angiography was not inferior to ventilation–perfusion lung scanning for ruling out PE JF - Evidence Based Medicine JO - Evid Based Med SP - 117 LP - 117 DO - 10.1136/ebm.13.4.117 VL - 13 IS - 4 A2 - , Y1 - 2008/08/01 UR - http://ebm.bmj.com/content/13/4/117.abstract N2 - D R AndersonDr D R Anderson, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada; david.anderson@dal.caDesign:randomised, controlled, non-inferiority trial.Allocation:concealed.*Blinding:blinded (clinicians, outcome assessors during initial assessment, and adjudication committee).*Setting:outpatient clinics, emergency departments, and inpatient units of 5 academic healthcare centres in Canada and the USA.Patients:1417 patients ⩾18 years of age (mean 53 y, 62% women) who presented with signs and symptoms of acute pulmonary embolism (PE; acute onset of new or worsening shortness of breath, chest pain, haemoptysis, pre-syncope, or syncope), with or without signs of deep venous thrombosis (DVT); and were assessed to be clinically likely (Wells model score ⩾4.5) or unlikely (score <4.5) to have PE but with a positive D-dimer test. Exclusion criteria included PE or DVT diagnosis in the previous 3 months; unchanged pulmonary symptoms in the previous 2 weeks; need for … ER -