TY - JOUR T1 - Review: medical therapy with calcium channel blockers or α blockers helps patients to pass urinary stones JF - Evidence Based Medicine JO - Evid Based Med SP - 15 LP - 15 DO - 10.1136/ebm.12.1.15 VL - 12 IS - 1 A2 - , Y1 - 2007/02/01 UR - http://ebm.bmj.com/content/12/1/15.abstract N2 - Hollingsworth JM, Rogers MA, Kaufman SR, et al. Medical therapy to facilitate urinary stone passage: a meta-analysis. Lancet 2006;368:1171–9.OpenUrlCrossRefPubMedWeb of Science 
 
 Q In patients with urolithiasis, are calcium channel blockers or α blockers more effective than standard therapy for helping patients pass urinary stones? Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★★☆ Emergency care ★★★★★★☆ Surgery—urology ★★★★★☆☆ Data sources: Medline, PREMEDLINE, CINAHL, EMBASE/Excerpta Medica, abstracts from annual meetings, study authors, and drug manufacturers. Study selection and assessment: randomised controlled trials (RCTs) that evaluated calcium channel blockers or α blockers as the main treatment for ureteral stone disease (mean size 3.9–7.8 mm) and had ⩾1 week follow up (range 15–48 d). Studies were excluded if medical therapy was an adjunct to surgery. 9 RCTs (n = 693, mean age range 34–47 y, 25% to 60% women) met the selection criteria. In 3 RCTs, corticosteroids were given to the treatment groups with the calcium channel blocker nifedipine. Non-steroidal anti-inflammatory drugs were given to both treatment … ER -