TY - JOUR T1 - Review: intravenous metoclopramide is better than placebo for reducing pain in acute migraine in the emergency department JF - Evidence Based Medicine JO - Evid Based Med SP - 83 LP - 83 DO - 10.1136/ebm.10.3.83 VL - 10 IS - 3 A2 - , Y1 - 2005/06/01 UR - http://ebm.bmj.com/content/10/3/83.abstract N2 - Colman I, Brown MD, Innes GD, et al. Parenteral metoclopramide for acute migraine: meta-analysis of randomised controlled trials. BMJ 2004;329:1369–73.OpenUrlAbstract/FREE Full Text 
 
 Q In patients with acute migraine, is metoclopramide more effective than a control intervention for reducing symptoms? Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Neurology ★★★★★★☆ Emergency medicine ★★★★☆☆☆ Data sources: Medline; EMBASE/Excerpta Medica; LILACS; CINAHL; Cochrane Central Register of Controlled Trials; neurology, headache, and emergency medicine conference proceedings (1998–2004); clinical practice guidelines; websites; theses or dissertations; reference lists; and experts in the field. Study selection and assessment: randomised controlled trials (RCTs) that compared parenteral metoclopramide with placebo, other antiemetics [AEs], non-AEs, or other antimigraine [AM] regimens in adults with an acute migraine in an emergency department (ED) or headache clinic, and distinguished migraine from other types of headaches. Study quality was assessed. Outcomes: complete relief of headache, significant reduction in headache pain (from moderate or severe to mild or none), and reduction in headache pain on the basis of a 10 … ER -