TY - JOUR T1 - Evidence-based medicine targets the individual patient, part 2: guides and tools for individual decision-making JF - Evidence Based Medicine JO - Evid Based Med SP - 130 LP - 131 DO - 10.1136/ebm.13.5.130-a VL - 13 IS - 5 AU - Dirk Bassler AU - Jason W Busse AU - Paul J Karanicolas AU - Gordon H Guyatt Y1 - 2008/10/01 UR - http://ebm.bmj.com/content/13/5/130.2.abstract N2 - Despite some suggestions to the contrary,1 2 evidence-based decision-making puts the individual patient on centre stage. In part 1 of this commentary,3 we first described the range of issues that clinicians should consider when applying randomised controlled trial (RCT) results to ensure appropriately individualised care (figure). Second, we have shown how clinicians can use results of prognostic studies and RCTs to determine each patient’s risk of the adverse events that treatment is designed to prevent, and thus each patient’s likely absolute benefit.3 In part 2 of this commentary we will describe additional evidence-based medicine (EBM) guides and tools that advance individual decision-making.Even if the overall relative summary treatment effect reported in a clinical trial suggests benefit, there may be … ER -