TY - JOUR T1 - A probiotic drink prevented diarrhoea and <em>Clostridium difficile</em> infection in older patients taking antibiotics JF - Evidence Based Medicine JO - Evid Based Med SP - 46 LP - 46 DO - 10.1136/ebm.13.2.46 VL - 13 IS - 2 A2 - , Y1 - 2008/04/01 UR - http://ebm.bmj.com/content/13/2/46.abstract N2 - M HicksonDr M Hickson, Charing Cross Hospital, London, UK; mary.hickson@imperial.nhs.ukStudy design:randomised placebo-controlled trial.Allocation:concealed.*Blinding:blinded (patients, {healthcare providers, data collectors, outcome assessors, and data analysts, and data safety and monitoring committee}†).*Setting:3 hospitals in London, UK.Patients:135 patients &gt;50 years of age (mean age 74 y, 54% women) who were receiving antibiotics (single or multiple, oral or intravenous) and were able to take food and drinks. Exclusion criteria included diarrhoea on admission or recurrent diarrhoea; bowel pathology that could cause diarrhoea; intake of high-risk antibiotics (ie, clindamycin, cephalosporins, or aminopenicillins) or &gt;2 courses of other antibiotics in the past 4 weeks; severe life-threatening illness; immunosuppression; bowel surgery; artificial heart valve; history of rheumatic heart disease or infective … ER -