TY - JOUR T1 - Manual physical therapy and exercise improved function in osteoarthritis of the knee JF - Evidence Based Medicine JO - Evid Based Med SP - 145 LP - 145 DO - 10.1136/ebm.5.5.145 VL - 5 IS - 5 A2 - , Y1 - 2000/09/01 UR - http://ebm.bmj.com/content/5/5/145.abstract N2 - (2000) Ann Intern Med 132, 173. Deyle GD, Henderson NE, Matekel RL, et al.. Effectiveness of manual physical therapy and exercise in osteoarthritis of the knee. A randomized, controlled trial.. Feb 1;. :. –81.OpenUrlPubMedWeb of Science
 
 QUESTION: In patients with osteoarthritis of the knee, how effective is manual physical therapy and exercise in decreasing pain and stiffness and increasing function and walking distance? Randomised (allocation concealed*), blinded (outcome assessor),* controlled trial with 1 year follow up. Outpatient clinic of a US army medical centre in Fort Sam Houston, Texas. 83 patients (mean age 61 y, 59% women) who had osteoarthritis of the knee, no surgical procedure on either lower limb in the previous 6 months, and no physical impairment that would preclude study participation. 69 patients (83%) completed the treatment. Patients were allocated to manual physical therapy and exercise (n=42) or placebo (ultrasonography at a subtherapeutic intensity) (n=41) given … ER -