TY - JOUR T1 - Both weight-bearing and non–weight-bearing exercise improved function in patients with knee osteoarthritis JF - Evidence Based Medicine JO - Evid Based Med SP - 178 LP - 178 DO - 10.1136/ebm.14.6.178 VL - 14 IS - 6 A2 - , Y1 - 2009/12/01 UR - http://ebm.bmj.com/content/14/6/178.abstract N2 - Design:randomised controlled trial (RCT).Allocation:unclear allocation concealment.*Blinding:blinded (outcome assessors).*Setting:kinesiology laboratory in Taiwan.Patients:106 patients ⩾50 years of age (mean age 62 y, 69% women) who had bilateral knee osteoarthritis (OA) according to American College of Rheumatology criteria, radiographic changes (OA grade ⩽3, compatible with mild and moderate OA), chronic knee pain for ⩾6 months, and willingness to stop medication.Intervention:weight-bearing exercise (WBE) (n = 36), non-WBE (n = 35), or no exercise (n = 35). WBE was done in a sitting position, using an EN-Dynamic resistance device (Enraf-Nonius BV, The Netherlands). With 1 foot fixed on the pedal of the device, patients fully extended and then flexed the knee joint from 90° flexion. For non-WBE, … ER -