TY - JOUR T1 - Gemfibrozil reduced the risk for stroke in men with coronary heart disease and low concentrations of high-density lipoprotein cholesterol JF - Evidence Based Medicine JO - Evid Based Med SP - 175 LP - 175 DO - 10.1136/ebm.6.6.175 VL - 6 IS - 6 A2 - , Y1 - 2001/11/01 UR - http://ebm.bmj.com/content/6/6/175.abstract N2 - (2001) Circulation 103, 2828. Rubins HB, Davenport J, Babikian V, et al,. for the VA-HIT Study Group.. Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol. The Veterans Affairs HDL Intervention Trial (VA-HIT).. Jun 12;. :. –33.OpenUrlAbstract/FREE Full Text
 
 QUESTION: In men with coronary artery disease and low concentrations of high-density lipoprotein (HDL) cholesterol, is gemfibrozil effective for preventing stroke? Randomised {allocation concealed*}†, blinded {patients, outcome assessors, and study personnel}†,* placebo-controlled trial with mean 5.1 years of follow up (Veterans Affairs HDL Cholesterol Intervention Trial [VA-HIT]). 20 Veterans Affairs medical centres in the USA. 2531 men who were < 74 years of age (mean age 64 y) and had a confirmed diagnosis of coronary artery disease, an HDL cholesterol level < 1.03 mmol/l, a low-density lipoprotein cholesterol level < 3.6 mmol/l, and a triglyceride level < 3.39 mmol/l. Follow up was complete. 1264 men were allocated … ER -