TY - JOUR T1 - Review: selective serotonin reuptake inhibitors reduce symptoms in premenstrual syndrome JF - Evidence Based Medicine JO - Evid Based Med SP - 75 LP - 75 DO - 10.1136/ebm.6.3.75 VL - 6 IS - 3 A2 - , Y1 - 2001/05/01 UR - http://ebm.bmj.com/content/6/3/75.abstract N2 - (2000) Lancet 356, 1131. Dimmock PW, Wyatt KM, Jones PW, et al.. Efficacy of selective serotonin-reuptake inhibitors in premenstrual syndrome: a systematic review.. Sep 30;. :. –6.OpenUrlCrossRefPubMedWeb of Science
 
 QUESTION: In women with severe premenstrual syndrome (PMS), are selective serotonin reuptake inhibitors (SSRIs) effective? Studies were identified by searching Medline (1966–99), EMBASE/Excerpta Medica (1988–98), PsycLIT (1974–97), CINAHL (1982–99), and the Cochrane Controlled Trials Register database; scanning the reference lists of identified articles; and contacting the manufacturers of SSRIs. Studies were selected if they were randomised, double blind, placebo controlled trials investigating SSRIs in the management of PMS. Data were independently extracted in duplicate on study design, patient characteristics, drug type and dose, outcome measures (primary outcome measure was reduction in overall PMS symptoms), and side effects. 15 studies met the selection criteria and involved 904 women (570 allocated … ER -