TY - JOUR T1 - Review: antidepressants improve symptoms of fibromyalgia JF - Evidence Based Medicine JO - Evid Based Med SP - 77 LP - 77 DO - 10.1136/ebm.6.3.77 VL - 6 IS - 3 A2 - , Y1 - 2001/05/01 UR - http://ebm.bmj.com/content/6/3/77.abstract N2 - (2000) J Gen Intern Med 15, 659. O'Malley PG, Balden E, Tomkins G, et al.. Treatment of fibromyalgia with antidepressants. A meta-analysis.. Sep;. :. –66.OpenUrlCrossRefPubMedWeb of Science
 
 QUESTION: Are antidepressants efficacious in the treatment of fibromyalgia? Studies in any language were identified by searching Medline (1966 to June 1999), PsycLIT (1974–98), and EMBASE/Excerpta Medica (1974–98) with the terms fibromyalgia, fibrositis, and fibromyositis combined with various terms for antidepressive agents (including specific drug names); the Cochrane Library Clinical Trials Registry and Database of Systematic Reviews; Federal Research in Progress to identify unpublished trials; and bibliographies of reviewed articles. Studies were selected if they were randomised, placebo controlled trials with at least 1 group receiving an antidepressant and if they reported measurable outcomes. Data were extracted on setting; country; dose, duration, and follow up of treatment; number of participants and demographics; assessment of comorbid disease; follow up losses; adverse effects; and outcomes. Methodological quality of individual trials was assessed using the Jadad scale. 13 trials (mean … ER -