TY - JOUR T1 - Omeprazole was better than cisapride or placebo for controlling heartburn at 4 and 8 weeks JF - Evidence Based Medicine JO - Evid Based Med SP - 59 LP - 59 DO - 10.1136/ebm.5.2.59 VL - 5 IS - 2 A2 - , Y1 - 2000/03/01 UR - http://ebm.bmj.com/content/5/2/59.abstract N2 - (1999) BMJ 319, 550. Hatlebakk JG, Hyggen A, Madsen PH, et al,. on behalf of the Norwegian Heartburn Study Group.. Heartburn treatment in primary care: randomised, double blind study for 8 weeks.. Aug 28;. :. –3.OpenUrlAbstract/FREE Full Text
 
 QUESTION: In patients with heartburn, are omeprazole and cisapride effective for controlling symptoms? 8 week randomised (allocation concealed*), blinded (patients and outcome assessors),* controlled trial. 65 primary care practices in liaison with endoscopy units and pharmacies in Norway. {484}† patients who were 18 to 80 years of age (median age 47 y in the cisapride group, 49 y in the omeprazole group, 50 y in the placebo group; 52% men) and had had heartburn for ≥3 d/wk for ≥3 months during a 14 day run in period. Exclusion criteria were grade 2 or 3 oesophagitis; Barrett oesophagus; peptic ulcer disease; gallstone disease; oesophagogastric surgery; use of prokinetic, … ER -