TY - JOUR T1 - Risk for mother to child HIV-1 infection was increased by breast feeding JF - Evidence Based Medicine JO - Evid Based Med SP - 177 LP - 177 DO - 10.1136/ebm.5.6.177 VL - 5 IS - 6 A2 - , Y1 - 2000/11/01 UR - http://ebm.bmj.com/content/5/6/177.abstract N2 - (2000) JAMA 283, 1167. Nduati R, John G, Mbori-Ngacha D. , et al.. Effect of breastfeeding and formula feeding on transmission of HIV-1. A randomized clinical trial.. Mar 1;. :. –74.OpenUrlCrossRefPubMedWeb of Science
 
 QUESTION: In the infants of HIV-1 infected women, does formula feeding instead of breast feeding reduce the rate of HIV-1 transmission and mortality? Randomised (allocation concealed*), blinded (investigators to interim results),* controlled trial with 2 year follow up. 4 antenatal clinics in Nairobi. 425 HIV-1 infected pregnant women (mean age 23 y) who resided in Nairobi and had access to municipally treated water. 401 mother-infant pairs (94%) were included in the analysis. Women were allocated to breast feed (n=212) or formula feed (n=213) their infants. Women in the formula feed group were told to feed their infant with a cup and had to demonstrate proper formula preparation and cup feeding to a visiting nurse. Infant HIV-1 infection and mortality … ER -