TY - JOUR T1 - Spacers made from sealed cold-drink bottles were as effective as conventional spacers in children with acute asthma JF - Evidence Based Medicine JO - Evid Based Med SP - 79 LP - 79 DO - 10.1136/ebm.5.3.79 VL - 5 IS - 3 A2 - , Y1 - 2000/05/01 UR - http://ebm.bmj.com/content/5/3/79.abstract N2 - (1999) Lancet 354, 979; Zar HJ, Brown G, Donson H, et al.. Home-made spacers for bronchodilator therapy in children with acute asthma: a randomised trial.. Sep 18;. :. –82.OpenUrlCrossRefPubMedWeb of Science
 
 QUESTION: In children with acute asthma, are homemade spacers as effective as conventional ones for improving response to a β2 agonist given by metered dose inhaler? Randomised {allocation concealed*}†, blinded (outcome assessors),* controlled trial with 15 to 30 minute follow up. A children's hospital in South Africa. 88 children, 5 to 13 years of age (mean age 10 y, 60% boys, 50% moderate to severe airway obstruction [peak expiratory flow rate {PEFR} 20% to 59% of predicted normal value]), with a history of asthma, and presented with an acute asthma attack. Exclusion criteria were inability to use a metered dose inhaler (MDI) and spacer or to have pulmonary function tests with PEFR <20% of the predicted … ER -