TY - JOUR T1 - <span hwp:id="article-title-1" class="article-title">1 day of nitrofurantoin was not as effective as 7 days for asymptomatic bacteriuria in pregnancy</span><span hwp:id="article-title-2" class="sub-article-title">Commentary</span> JF - Evidence Based Medicine JO - Evid Based Med SP - 113 LP - 113 DO - 10.1136/ebm.14.4.113 VL - 14 IS - 4 AU - Nicola Vousden AU - Andrew H Shennan Y1 - 2009/08/01 UR - http://ebm.bmj.com/content/14/4/113.abstract N2 - Design:randomised controlled trial.Allocation:concealed.*Blinding:blinded (patients, healthcare providers, data collectors, and outcome assessors).*Setting:antenatal clinics in 7 hospitals in Thailand, the Philippines, Vietnam, and Argentina.Patients:778 pregnant women (mean age 27 y) at 12–32 weeks of gestation who were diagnosed (by a 2-step screening process) as having asymptomatic bacteriuria caused by a micro-organism sensitive to nitrofurantoin. Women with symptoms of urinary tract infection (UTI), treatment of UTI in the current pregnancy, a condition requiring continuous steroid or antibiotic therapy, antibiotic hypersensitivity, or haematological disease (including glucose-6-phosphate dehydrogenase deficiency) were excluded.Intervention:nitrofurantoin, 100 mg orally twice daily, for 1 day (n = 386) or 7 days (n = 392). The 1-day group received placebo tablets after day 1 to … ER -