TY - JOUR T1 - Clopidogrel reduced recurrent ischaemic events in patients with previous cardiac surgery more than aspirin JF - Evidence Based Medicine JO - Evid Based Med SP - 114 LP - 114 DO - 10.1136/ebm.6.4.114 VL - 6 IS - 4 A2 - , Y1 - 2001/07/01 UR - http://ebm.bmj.com/content/6/4/114.abstract N2 - (2001) Circulation 103, 363. Bhatt DL, Chew DP, Hirsch AT, et al.. Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery.. Jan 23;. :. –8.OpenUrlAbstract/FREE Full Text
 
 QUESTION: In patients with recent ischaemic stroke, recent myocardial infarction (MI), or peripheral arterial disease and previous cardiac surgery, is clopidogrel more effective than aspirin in reducing recurrent ischaemic events? Subgroup analysis of a randomised {allocation concealed*}†, blinded {patients, clinicians, outcome assessors, and statisticians}†* placebo controlled trial with 1–3 year follow up (mean 1.6 y) (Clopidogrel versus Aspirin in Patients at Risk of Ischemic Events [CAPRIE] study). {384 clinical centres in 16 countries}†. 1480 patients (mean age 64 y, 84% men, 96% white) with recent stroke or MI or peripheral arterial disease who … ER -