TY - JOUR T1 - BMI <22.5 and >25 predicted higher overall mortality in adults JF - Evidence Based Medicine JO - Evid Based Med SP - 152 LP - 152 DO - 10.1136/ebm.14.5.152 VL - 14 IS - 5 A2 - , Y1 - 2009/10/01 UR - http://ebm.bmj.com/content/14/5/152.abstract N2 - What is the association between body mass index (BMI) and mortality in adults? Included studies provided data on BMI and death. Analyses excluded people with BMI <15 kg/m2 or ⩾50 kg/m2 or history of heart disease or stroke. Outcomes were overall mortality and cause-specific mortality (>50 specific causes of death). {Medline, EMBASE/Excerpta Medica, and conference abstracts were searched and investigators were contacted}* for prospective studies. 57 studies (n = 894 576, mean age 46 y, 61% men) met the selection criteria. BMI ranging from 22.5 to 25 kg/m2 was associated with lowest overall mortality. In people with BMIs of 25–50 kg/m2, each 5 kg/m2 higher BMI was associated with 30% higher overall … ER -