TY - JOUR T1 - Review: evidence on the effectiveness of interventions to assist patient adherence to prescribed medications is limited JF - Evidence Based Medicine JO - Evid Based Med SP - 123 LP - 123 DO - 10.1136/ebm.8.4.123 VL - 8 IS - 4 A2 - , Y1 - 2003/07/01 UR - http://ebm.bmj.com/content/8/4/123.abstract N2 - (2002) JAMA 288, 2868. McDonald HP, Garg AX, Haynes RB.. Interventions to enhance patient adherence to medication prescriptions: scientific review.. ;. :. –79.OpenUrlCrossRefPubMedWeb of Science
 
 QUESTION: In non-addicted patients with medical or mental disorders, are interventions designed to assist adherence to self administered prescribed medications effective? Studies were identified by searching Medline, CINAHL, PsycLIT, SOCIOFILE, IPA, EMBASE/Excerpta Medica, and the Cochrane Library (all from 1967 to August 2001). Bibliographies of relevant articles were reviewed, and authors of included studies were contacted for additional trials. Studies were selected if they were unconfounded randomised controlled trials (RCTs) of interventions to improve adherence with self administered prescribed medications for a medical or psychiatric disorder, measured both medication adherence and treatment outcome, had ≥80% follow up of each group studied, and the duration of follow up for studies with positive initial findings was ≥6 months. Data were extracted on sample size, details of intervention strategies for adherence, details of treatment for the underlying medical or mental disorder, study quality, … ER -