TY - JOUR T1 - 1 day quadruple therapy was not inferior to 7 day triple therapy for eradication of <em>Helicobacter pylori</em> infection in dyspepsia JF - Evidence Based Medicine JO - Evid Based Med SP - 74 LP - 74 DO - 10.1136/ebm.9.3.74 VL - 9 IS - 3 A2 - , Y1 - 2004/05/01 UR - http://ebm.bmj.com/content/9/3/74.abstract N2 - Lara LF, Cisneros G, Gurney M, et al. One-day quadruple therapy compared with 7-day triple therapy for Helicobacter pylori infection. Arch Intern Med 2003;163:2079–84.OpenUrlCrossRefPubMedWeb of Science 
 
 Q In patients with dyspepsia, is 1 day quadruple therapy non-inferior to 7 day triple therapy for eradication of Helicobacter pylori infection? Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Gastroenterology ★★★★★☆☆ Infectious disease ★★★☆☆☆☆ Design: randomised controlled trial. Allocation: {concealed*}†. Blinding: unblinded.* Follow up period: 5 weeks. Setting: ambulatory internal medicine clinics of 2 university affiliated hospitals in Canton, Ohio, USA. Patients: 160 patients aged ⩾18 years (mean age 50 y, 57% women) who had dyspepsia and H pylori infection, a Glasgow Dyspepsia Severity Score (GDSS) ⩾3 (score range 0–20), and a positive carbon 14 urea breath test result. Exclusion criteria included previous treatment of H pylori infection, pregnancy, personal or family history of gastrointestinal malignancy, antibiotic therapy in the previous 6 weeks, previous gastric surgery, and hepatic insufficiency. Interventions: 1 day regimen of 2 … ER -