TY - JOUR T1 - Network meta-analysis shows that prostaglandin inhibitors and nifedipine are best short-term tocolytics for preterm delivery JF - Evidence Based Medicine JO - Evid Based Med SP - 182 LP - 183 DO - 10.1136/eb-2012-101128 VL - 18 IS - 5 AU - Adi Abramovici AU - Sheri Jenkins Y1 - 2013/10/01 UR - http://ebm.bmj.com/content/18/5/182.abstract N2 - Commentary on: Haas DM, Caldwell DM, Kirkpatrick P, et al. Tocolytic therapy for preterm delivery: systematic review and network meta-analysis. BMJ 2012;345:e6226.OpenUrlAbstract/FREE Full Text Preterm birth is the leading cause of perinatal morbidity and mortality and a major source of healthcare costs. Despite advances in obstetrical care, the incidence of preterm birth is at an all-time high and may be rising due to increasing rates of advancing maternal age, maternal medical conditions, assisted reproductive technology and multiple gestations.1 Prevention of preterm birth and its associated neonatal morbidity and mortality are major concerns and a significant focus for obstetrical research. Tocolytics have not been shown to decrease the risk for preterm birth, but they have been associated with a short-term delay in delivery. Therefore, the primary goal of tocolysis is to allow administration of glucocorticoids in order to reduce the risk … ER -