TY - JOUR T1 - Population benefits of HPV vaccination for boys: a complex equation JF - Evidence Based Medicine JO - Evid Based Med SP - 118 LP - 119 DO - 10.1136/ebmed-2011-100433 VL - 17 IS - 4 AU - David Gabriel Regan Y1 - 2012/08/01 UR - http://ebm.bmj.com/content/17/4/118.abstract N2 - Commentary on: Brisson M, van de Velde N, Franco EL, et al. Incremental impact of adding boys to current human papillomavirus vaccination programs: role of herd immunity. J Infect Dis 2011;204:372–6.OpenUrlAbstract/FREE Full Text With the licensing and subsequent roll-out of female vaccination against human papillomavirus (HPV) in many, mainly high-resource settings, there has emerged a chorus of voices advocating vaccination for males. The interest in male vaccination has intensified with the publication of early observational data from Australia heralding the effectiveness of vaccination when high coverage is achieved1 ,2 and the results of clinical trials demonstrating efficacy against infection and disease in males.3 A recent mathematical modelling study by Brisson et al provides estimates of the potential long-term benefits of HPV vaccination, including the incremental benefit of adding male vaccination to an existing female-only programme. A previously described4 individual-based transmission-dynamic model was developed and calibrated to sexual behaviour and HPV … ER -