TY - JOUR T1 - Calcium supplements may increase the risk of cardiovascular events in postmenopausal women JF - Evidence Based Medicine JO - Evid Based Med SP - 16 LP - 17 DO - 10.1136/ebm.2011.100113 VL - 17 IS - 1 AU - Barbara J Boucher Y1 - 2012/02/01 UR - http://ebm.bmj.com/content/17/1/16.abstract N2 - Commentary on: Bolland MJ, Grey A, Avenell A, et al. Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis. BMJ 2011;342:d2040.OpenUrlAbstract/FREE Full Text Calcium supplementation is widely used for osteoporosis (OP) prevention and treatment. Many women buy calcium supplements, ±vitamin D. The authors' earlier randomised controlled trial (RCT) and meta-analysis suggests that calcium supplementation increases cardiovascular-event risks provoked controversy, as has this report.1,–,3 The ‘Women’s Health Initiative Calcium/vitamin D Supplementation Study' (WHICaD) limited access data set of 36 282 community-dwelling postmenopausal women comparing calcium plus vitamin D with placebo over 7 years was re-examined for effects of personal (preprotocol) calcium usage, adjusted for other cardiovascular disease (CVD) risk factors, followed by meta-analysis of the data on non-personal calcium users and from eight similar studies (some data previously unpublished; … ER -