TY - JOUR T1 - Nucleic acid amplification tests of self-taken vulvovaginal swabs are more sensitive than clinician taken endocervical culture for gonorrhoea JF - Evidence Based Medicine JO - Evid Based Med SP - e46 LP - e46 DO - 10.1136/eb-2013-101251 VL - 18 IS - 5 AU - Beverley Lawton AU - Collette Bromhead Y1 - 2013/10/01 UR - http://ebm.bmj.com/content/18/5/e46.abstract N2 - Commentary on Stewart CM, Schoeman SA, Booth RA, et al. Assessment of self taken swabs versus clinician taken swab cultures for diagnosing gonorrhoea in women: single centre, diagnostic accuracy study. BMJ 2012; 345: e8107.OpenUrlAbstract/FREE Full Text Neisseria gonorrhoea (NG) has a low prevalence in most developed countries. NG causes significant pathology including pelvic inflammatory disease, neonatal transmission and increased susceptibility to HIV. It has been usual practice to detect NG by culturing endocervical and urethral specimens that are obtained by pelvic examination. However, there is a significant false-negative rate. The use of nucleic acid amplification tests (NAATs) increases detection of NG.1 This study examines the diagnostic accuracy of NAATs for gonorrhoea detection by self-taken vulvovaginal swabs compared with culture of clinician taken urethral and endocervical samples. The participants (n=3973) … ER -