TY - JOUR T1 - In patients with persistent atrial fibrillation complex ablation techniques were no better than pulmonary vein isolation alone in preventing recurrent atrial fibrillation JF - Evidence Based Medicine JO - Evid Based Med SP - 175 LP - 175 DO - 10.1136/ebmed-2015-110238 VL - 20 IS - 5 AU - Martin Manninger AU - Daniel Scherr Y1 - 2015/10/01 UR - http://ebm.bmj.com/content/20/5/175.abstract N2 - Commentary on: Verma A, Jiang CY, Betts TR, et al., STAR AF II Investigators. Approaches to catheter ablation for persistent atrial fibrillation. N Engl J Med 2015;372:1812–22.OpenUrlCrossRefPubMedPulmonary vein isolation (PVI) is a well-established treatment for patients with paroxysmal atrial fibrillation (AF).1 ,2 Ablation of persistent AF (beyond 7 days) or longstanding persistent AF (>12 months) is less likely to result in permanent sinus rhythm.1 ,2 For this reason, additional ablation methods subsumed as ‘substrate modification’ are often combined with PVI. These methods include ablation of complex fractionated atrial electrograms (CFAEs) and/or creation of linear lesions within the left atrium.The study reported on a randomised trial … ER -