TY - JOUR T1 - Home blood pressure monitoring with patient-initiated drug titration reduces blood pressure in high-risk patients with hypertension JF - Evidence Based Medicine JO - Evid Based Med SP - 58 LP - 58 DO - 10.1136/ebmed-2014-110109 VL - 20 IS - 2 AU - Steven M Smith AU - Rhonda M Cooper-DeHoff Y1 - 2015/04/01 UR - http://ebm.bmj.com/content/20/2/58.abstract N2 - Commentary on: McManus RJ, Mant J, Haque MS, et al. Effect of self-monitoring and medication self-titration on systolic blood pressure in hypertensive patients at high risk of cardiovascular disease: the TASMIN-SR randomised clinical trial. JAMA 2014;312:799–808.OpenUrlCrossRefPubMedWeb of ScienceIn patients with uncomplicated hypertension, home blood pressure (BP) monitoring combined with medication self-titration has been shown to substantially reduce BP.1 It is unknown whether a similar intervention is effective in high-risk patients with hypertension.Patients (n=555) aged ≥35 years with a BP ≥130/80 mm Hg, but ≤180/100 mm Hg (treated with 0–3 antihypertensive drugs) and ≥1 high-risk condition were randomly assigned to home BP monitoring with patient-initiated drug titration (intervention arm) or standard care. In the intervention arm, patients and their general practitioner (GP) developed an individualised three-step titration plan at baseline. Patients then measured home BP daily for the first … ER -